Studies on mitotic gene conversion in Ustilago
نویسندگان
چکیده
منابع مشابه
Mitotic Gene Conversion in Yeast
In yeast, coincident gene conversion events involving the LEUl and TRPS loci (16 cM apart) occur at frequencies that re far greater than is expected for two independent acts of recombination. When a large plasmid (pJM53) is placed between these genes so that a direct repeat is produced, there is frequent loss of the insert among coincident convertants. Previous results strongly suggest that thi...
متن کاملCoincidence relations between gene conversion and mitotic recombination in Saccharomyces.
major attributes of mitotic gene conversion in Saccharomyces have been TEai led by ROMAN (1956a) and by KAKAR ( 1961) for heteroallelic diploids, while LINDEGREN (1953) , WINGE (1955) , and PAPAZIAN and LINDEGREN (1960) have investigated instances of aberrant segregation ratios in meiosis. Heteroallelic repair, or gene conversion, is essentially non-reciprocal in character. Three lines of evide...
متن کاملRevertant Mosaicism in Epidermolysis Bullosa Caused by Mitotic Gene Conversion
Mitotic gene conversion acting as reverse mutation has not been previously demonstrated in human. We report here that the revertant mosaicism of a compound heterozygous proband with an autosomal recessive genodermatosis, generalized atrophic benign epidermolysis bullosa, is caused by mitotic gene conversion of one of the two mutated COL17A1 alleles. Specifically, the maternal allele surrounding...
متن کاملRad52-independent mitotic gene conversion in Saccharomyces cerevisiae frequently results in chromosomal loss.
We have examined spontaneous, interchromosomal mitotic recombination events between his4 alleles in both Rad+ and rad52 strains of Saccharomyces cerevisiae. In Rad+ strains, 74% of the His+ prototrophs resulted from gene conversion events without exchange of flanking markers. In diploids homozygous for the rad52-1 mutation, the frequency of His+ prototroph formation was less than 5% of the wild...
متن کاملMitotic and meiotic gene conversion of Ty elements and other insertions in Saccharomyces cerevisiae.
We examined meiotic and mitotic gene conversion events involved in deletion of Ty elements and other insertions from the genome of the yeast Saccharomyces cerevisiae. We found that Ty elements and one other insertion were deleted by mitotic gene conversion less frequently than point mutations at the same loci. One non-Ty insertion similar in size to Ty, however, did not show this bias. Mitotic ...
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ژورنال
عنوان ژورنال: Genetical Research
سال: 1966
ISSN: 0016-6723,1469-5073
DOI: 10.1017/s0016672300010181